The Science Behind: Product Development


Nerium SkinCare, Inc. develops, formulates, and manufactures for the consumer a line of “first of its class” botanical skincare products for topical application. Nerium SkinCare’s product development is founded on the technology, core science, and continuing research of Nerium Biotechnology, Inc. at leading medical institutions, using the latest scientific methods and technology.


Nerium SkinCare’s unique product formulations utilize a new patent-pending extraction technology NBio-PLÇ™, and the resultant new Nerium extract, NAE-8™. This innovation combines the properties of Nerium oleander and Aloe Vera and provides the opportunity to develop an ever-expanding flow of unique dermal/topical skincare applications/products.


Nerium SkinCare’s product development starts with the science initiated at its USA-based environmentally responsible and earth-friendly farming operations, where fields of Nerium oleander plants provide the raw material (biomass) for the botanical extract NAE-8. Transitioning from the nursery environment to commercial farming, the company now has over twelve years of scientific experience commercially growing the Nerium oleander plant to provide a dedicated and renewable biomass resource reserved exclusively for biotechnology research, product development, and production. This provides the company the ability to control the entire process from seedlings through production to ensure quality and consistency.


The company’s product development and formulation is based on the philosophy of evidence-based research. Dennis Knocke, CEO of Nerium Biotechnology, says, “We strongly believe in sustainable, honest, and accountable practices, as well as maximum disclosure of information to meet regulatory compliance. We are committed and dedicated to offering skincare solutions that are based on proven science and actual customer success. We will not release any product without safety and evidence-based proof of product performance.”


As a commitment to quality, Nerium SkinCare does not compromise on what goes into its products. The quality of Nerium SkinCare’s products is a direct result of the investment into the people, scientific research, new technology, natural farming methods, biomass processing, product formulation, manufacturing and product safety testing


With the development of Nerium SkinCare’s first skincare product, NeriumAD Age-Defying Treatment, a night cream, Nerium SkinCare reviewed multiple distribution and marketing channels for this new product launch. “Our team’s dedicated research determined that relationship marketing was the premier method to inform and educate consumers. All roads in determining how best to accomplish this led us directly to Jeff Olson, who is a recognized leader in the relationship marketing industry,” says Knocke. “Olson immediately understood and envisioned the opportunity and potential, his recognition of the history, science, barrier of entry for competition, control of the supply-line (Farm), patent-pending extraction process (NBio-PLÇ™ – Nerium/Aloe), new ingredient (NAE-8™), the potential for development of a broad range of products, and product safety/testing results led to the formation of Nerium International, LLC, founded and formed by Olson, and a dynamic new partnership.


Today, product distribution and marketing of Nerium Skincare’s products is provided for through an exclusive licensing partnership between Nerium Skincare, Inc. and Nerium International, LLC. “We are very excited with this new business relationship with Jeff Olson and are well positioned to build a major global brand.

In addition, Nerium SkinCare is committed to expanding this relationship globally,” says Knocke.

“What has excited Nerium SkinCare the most with the Nerium International partnership is the business model and the level of expertise and experience that Jeff Olson brings to the table, as it is not his first time to discover a unique opportunity from which millions of consumers benefit,” states Knocke. “Olson has assembled a corporate team that is recognized as leaders with over 150 collective years of industry experience and, naturally, proven leadership and management skills. Nerium International has a proven marketing system with proprietary internet and software design that provides unrivaled capabilities. From a quick review of Nerium International’s website, it is easy to see that Nerium International provides the necessary tools and a very strong foundation for their Brand Partners’ [distributors’] success. Brand Partners are provided with personal and professional development opportunities, a personalized website with internet management and business tools, top quality marketing material, training and the internet capability to develop a strong social community.”


“Nerium SkinCare firmly believes that the independent business men and women who join Nerium International as Independent Brand Partners have a powerful opportunity for financial success in their own business, marketing an exclusive and unique product line providing benefit to the end user, with recognition and rewards along the way,” says Knocke. “With the market launch of NeriumAD in the United States, the first eight months of this process has been very exciting and rewarding for Nerium Skincare. We have observed Nerium International experience month over month of sales increases and increasing market acceptance. The massive growth experienced from the hard work and efforts provided by Nerium International and the Independent Brand Partners can only be described as phenomenal. The future looks bright as we continue to strengthen this relationship, add to our team, build additional product line, and expand internationally,” finishes Knocke.


“We are committed and dedicated to offering skincare solutions that are based on proven science and actual customer success. We will not release any product without safety and evidence-based proof of product performance,” says Knocke.


About Dennis R. Knocke, Chief Executive Officer and Chairman of the Board of Directors:

Mr. Knocke attended Sam Houston State University in Huntsville, Texas. He has successfully founded and operated several start-up healthcare companies that were acquired by national and international business entities listed on the New York and London stock exchanges. Mr. Knocke was previously President of Bexar Credentials Verification, Inc., a start-up software technology company whose principals included the Bexar County Medical Society, the Texas Medical Liability Trust, and Florida Physicians Insurance Company. Prior to transitioning to Nerium Biotechnology, Inc., he served as Chief Operating Officer (COO) for Phoenix Biotechnology, Inc.


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  • NeriumShaw

    The Science behind NeriumAD is wonderful and well researched. Nerium puts safety and proven results as a high priority.

  • Zoe Morris

    The Science behind Nerium AD is incredible. Most products are based on verbal surveys where Nerium AD has been scientifically proven to work as well.

  • Keely Gaston Nations

    I love hearing how Nerium AD was created. The research proves time and time again how amazing this product is.

  • Misty

    It’s interesting to learn about how NeriumAD was created. I love how open and honest this company is – sharing all aspects of the development of Nerium!

  • Chelsea

    Nerium SkinCare has been an awesome business partner with Nerium International! Love the partnership and the products that result from it!

  • Monica F

    Nerium is backed by science, and results that are amazing.

  • J Branch

    NeriumAD is certainly not a “me too” product. The science behind NeriumAD is rock solid and independently confirmed. Well done Nerium!

  • Denise V

    I love that Nerium has great testing and evidence-based research behind NeriumAD.

  • David C

    Neriums committment to Science and testing solidifies their repuatation as a world class organization

  • pershevia smith

    It is very exciting to learn the science and creativity behind the NeriumAD formula!!

  • Trevor

    Nerium has the best partnership of a scientific research company and an amazing relationship marketing company. The two together ensure NeriumAD is a unmatchable product with a powerful marketing channel to build your business.

  • Kayla W

    Nerium has impressive science behind their product! The emphasis that is placed on the science and safety is incredible!

  • dennis windsor

    Nerium has great scientific partners! Our breakthrough Scince really helps set us apart in a very crowded marketplace!!

  • Quintessential

    The fact that Nerium takes the time to have the product checked from many ends for safety speaks volume about the company and the ethics it holds dear. The science and time given is enough to prove that the company is real and gives reals results.

  • diedre townsend-taylor

    is Very Very committed to providing the best, for Brand Partners and PC’s.
    Nerium believes in educating one’s self before entering into the unknown.
    Nerium Provides that education and top of the line product to allow not just
    the Brand partners but everyone involved a successful way of life and new
    beautiful looks. Thank you Nerium for your commitment

  • Susan Kern Centeno

    I love how Nerium has gone to great lengths to test the safety of their product. I feel very fortunate and comfortable using it and recommending Nerium to my friends and family.

  • Shannon Bagaus Rothstein

    Nerium just keeps getting better and better. The More I learn about the real science and the real people behind NeriumAD the more I am impressed! It just keeps getting better and better!

  • Amanda Jones Thompson

    LOVE! LOVE! LOVE that Nerium is so committed to safety and testing of their product. Not only do we deliver real results that people see in the mirror daily but we have science and transparency of science to prove the results are real.

  • Jen Hassenpflug-Soliz

    Thank You Nerium for sharing this information with us!

  • Christine

    The Safety and Science behind Nerium is why we are all seeing amazing results and changing lives everyday.

  • Lisa Hicks Clark

    Nerium is incredible for those that like natural products. The results are incredible… my friend told me my skin got better improvements than lasering could have ever produced! Love that I get My Nerium for FREE!!!!

  • Lisa Hicks Clark

    Great Nerium Information… I have been using for about 10 months now and my skin is AMAZING!!!!!

  • Puya Ghandian

    This information was extremely detailed and very helpful!

  • Pingback: The Science Behind: Product Development at Nerium International


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